High Throughput (Modular LC Standard Autosampler)

This section is shown only when the function is supported.

Enable Optimization

Optimization provides faster throughput of samples by allowing the preparation of the next injection while the current injection is being completed. The net effect is that more samples are performed during a given period of time, although the actual individual injection times remain constant. When optimization is enabled, the next sample is taken up into the autosampler as the first sample is being injected.

Specify the time (in minutes) after injection when the optimization process should begin. Choose the type of optimization using the option buttons.

Prefetch Vial

Choose Prefetch Vial to specify that the next sample is fetched by the gripper while the current sample is running.

Overlap Injection Cycle

Select Overlap Injection Cycle to specify that the next sample is fetched and loaded into the sample loop while the current sample is running.

The parameters for overlapped injection are specified as part of the method. There are no parameters for overlapped injection to be specified in the sequence/worklist table. However, there are important restrictions to using Overlapped Injection in sequences/worklists:

  • In the sequence/worklist, all injections where you wish to use overlapped injection must use the same method. This is because the method provides the necessary information for sample location and volume to trigger the events leading up to the next injection while the current injection is being completed. Where different methods are specified, the sequence/worklist continues, but the overlapped injection is ignored.

  • Control samples may NOT be used. If a control sample is inserted in the sequence/worklist, there will be no overlapping in the following injections because the Control sample might fail and the sequence/worklist would then be stopped.

  • Important restrictions for using Pretreatment/Injector Programs with Overlapped Injection:

    • Overlapped Injection can handle pre-injection tasks but not post-injection tasks. This is because the next sample is being prepared for injection during the current injection.

    • The command INJECT may not be used in an injector program with Overlapped Injection.