Terms related to 2D-LC

Term	Definition
2D-LC	Two-dimensional liquid chromatography
1D	One-dimensional 1D-LC is the classical (one-dimensional) chromatography, which provides one-dimensional data. Usually, you would not even think about dimensions in the 1D world.
¹D	First dimension For example, a ¹D column is the column used in the first dimension, and a ¹D chromatogram is the chromatogram acquired for the first dimension.
2D	Two-dimensional 2D-LC is two dimensional chromatography, which provides two-dimensional data. Two-dimensional data is data that has a first and a second dimension. For example, 2D results can have chromatograms and peaks in each dimension. A 2D peak has a retention time in each dimension. 2D peaks are peaks in the two-dimensional contour plot.
²D	Second dimension For example, a ²D pump is a pump installed in the second dimension. The ²D retention time is the retention time in the second dimension chromatogram, or the weighted averaged retention time for the second dimension in a two-dimensional peak. ²D peaks are peaks in ²D cut chromatograms.
2D compound	Two-dimensional compound, with a two-dimensional peak having a ¹D retention time and a ²D retention time.
LCxLC	Comprehensive 2D-LC
LC-LC	Heart-cutting 2D-LC
MHC	Multiple Heart-cutting
HiRes	High-Resolution Sampling

2D-LC

Two-dimensional liquid chromatography

1D

One-dimensional

1D-LC is the classical (one-dimensional) chromatography, which provides one-dimensional data. Usually, you would not even think about dimensions in the 1D world.

¹D

First dimension

For example, a ¹D column is the column used in the first dimension, and a ¹D chromatogram is the chromatogram acquired for the first dimension.

2D

Two-dimensional

2D-LC is two dimensional chromatography, which provides two-dimensional data.

Two-dimensional data is data that has a first and a second dimension.

For example, 2D results can have chromatograms and peaks in each dimension. A 2D peak has a retention time in each dimension. 2D peaks are peaks in the two-dimensional contour plot.

²D

Second dimension

For example, a ²D pump is a pump installed in the second dimension. The ²D retention time is the retention time in the second dimension chromatogram, or the weighted averaged retention time for the second dimension in a two-dimensional peak. ²D peaks are peaks in ²D cut chromatograms.

2D compound

Two-dimensional compound, with a two-dimensional peak having a ¹D retention time and a ²D retention time.

LCxLC

Comprehensive 2D-LC

LC-LC

Heart-cutting 2D-LC

MHC

Multiple Heart-cutting

HiRes

High-Resolution Sampling