To be able to carry out the procedure as described, you need the privilege Processing Method > Edit signal parameters . Privileges are configured in the Control Panel. If the project enforces method approval, the method status must be Generic. For details, see Method approval. You have acquired the signal for a blank run, that is, a solution with the same solvent, additives, etc. as the samples, but without the compounds of interest. You have acquired the blank run with the same detector (same signal name or same signal description) as the samples. For non-MS signals, the signal is typically the short name of a detector, for example, DAD1A. The signal description then includes more details, for example, DAD1A, Sig=235,10 Ref=550,60. By matching the one or the other, you define how flexible the processing method can be used with different acquisition methods.
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