How does the Integration Optimizer evaluate your data?

When you click Next in step 1 of the Integration Optimizer, the Integration Optimizer expert system evaluates the data as follows:

1. Integrate

   The system integrates the selected signal in the background, using the ChemStation integrator with the highest possible sensitivity. As a result, a list of any possible peaks is stored internally.

2. Get smallest peak

   • If you have set a smallest peak range: The system checks if there are more than three data points available and if there is any peak included. It uses this peak as the smallest peak.

   • If you have not set a smallest peak range: The system sorts all previously stored peaks by size. It gets the smallest peak by eliminating all noise peaks. It uses a K-clustering algorithm and gaussian bell curve to separate noise from real peaks.

3. Get initial integration parameters

   • ChemStation integrator: The system sets Height reject to 80% of the smallest peak's height. It calculates the other parameters using statistical methods, and uses default values for the Advanced integration parameters.

   • EZChrom integrator: The system sets Minimum area to 80% of smallest peak's area. It sets the Width based on the data rate, and calculates the other parameters using statistical methods.

4. Suppress solvent peak

   The system determines if a solvent peak is present, and sets the integration parameters so that the solvent peak is suppressed.

5. Timed events

   The system creates timed events based on the integration range that you have selected in step 1.

6. Integrate again

   The system integrates the signal again with the current settings.

7. Slider ranges

   The system calculates the relevant slider ranges and slider types (linear or curved, continuous or stepwise). It uses the selected injection as a basis.