Calculation of exponential curve for skims

The following equation is used to calculate an exponential, new exponential, or gaussian skim:

Hb(tR) = H0 * exp (- B * (tR - t0)) + A * tR + C

where

Hb

Height of the exponential skim at time tR

H0

Height (above baseline) of the start of the skim (different estimates for exponential and gaussian skim)

B

Decay factor (different estimates for exponential and gaussian skim)

t0

Time corresponding to the start of the skim (different estimates for exponential and gaussian skim)

tR

Retention time

A

Slope of the baseline of the parent peak

C

Offset of the baseline of the parent peak (different estimates for exponential and gaussian skim)

 

Values used to calculate an exponential skim