UV impurity check

An impurity check assesses whether a peak is pure or contains impurities. This assessment is based on the comparison of spectra recorded during the elution of the peak. After applying a baseline correction, the spectrum at the peak apex is compared with all significant spectra recorded in the peak. The application calculates a match factor that characterizes the degree of similarity of the spectra.

The application performs the following steps to evaluate UV impurities:

1. Per peak

   1. Noise calculation

   2. Determine significant spectra

2. Per spectrum:

   1. Background correction

   2. Match factor calculation

   3. Threshold calculation

3. Impurity evaluation