Use data from previous versions of OpenLab CDS

Data, methods, and reports created with previous versions of OpenLab CDS (2.0 or higher) can be continued to be used in OpenLab CDS 3.0. Methods may contain new functions, corresponding to their method configuration.

With MS compounds quantified on EIC or SIM signals using an extraction window:

• Due to dynamic signal change (re-centering), the baseline of the EIC or SIM peak may shift slightly. As a consequence, the results might vary between CDS versions before v3.0 and version 3.0 or later.

With MS compounds using qualifiers:

• For methods coming from v2.6 or earlier (even for data acquired later) the reference signal for qualifier calculations must be verified. Agilent recommends to update the qualifier response ratios (see Update qualifier responses, MS qualifier calculations)

Updated MS peak purity algorithm

• In OpenLab CDS v3.0, the MS peak purity algorithm has been updated to improve peak integration. Due to the changed algorithm, some MS Purity results may differ when data from previous OpenLab CDS versions is reprocessed in v3.0. To minimize differences, avoid using fast polarity switching (positive and negative polarity switching with the same time segment), and use sufficient data rates to get correctly defined peak shapes.

Names of MS compounds:

• Before OpenLab CDS 3.0, two compounds with the same name and signal (m/z) but different retention times were allowed if an extraction window was enabled (the extraction window was part of the signal name). As of rev. 3.0, this is no longer allowed. These compounds names need to be adjusted to avoid duplicates.

  

  Figure: Isomers example in OpenLab CDS 2.8

  

  Figure: Isomers example from OpenLab CDS 2.8 opened in 3.0